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Original Article |

Hinged Forearm Split-Thickness Skin Graft for Radial Artery Fasciocutaneous Flap Donor Site Repair FREE

Kofi Boahene, MD; Jeremy Richmon, MD; Patrick Byrne, MD; Lisa Ishii, MD, MHS
[+] Author Affiliations

Author Affiliations: Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.


Arch Facial Plast Surg. 2011;13(6):392-394. doi:10.1001/archfacial.2011.65.
Text Size: A A A
Published online

Objective To present a modified technique in the harvest and application of split-thickness skin graft (STSG) from the primary flap donor site in forearm fasciocutaneous free flaps.

Methods A prospective review was performed on 16 consecutive patients who had undergone a radial forearm free flap procedure for reconstruction of head and neck defects with a hinged forearm STSG used to reconstruct the flap donor site defect.

Results Sixteen patients with a mean (SD) defect size of 53.7 (29.9) cm2 underwent the hinged STSG procedure. A hinged STSG was successfully harvested from all patients without disruption. Graft take was greater than 90% in all patients by postoperative day 7. A secondary skin graft donor site was avoided in all but 2 patients. Good color match of the deepithelialized flap with surrounding oral and pharyngeal mucosa was observed. Visible scarring along the graft hinge margin was absent. No bridging scars resulted from the deepithelialized flaps.

Conclusions The hinged STSG from the forearm is a reliable method of repairing radial forearm free flap donor site defects and offers the advantages of reduced suture line scarring, minimal STSG disruption, low or no secondary donor site morbidity, and good color match at the donor and recipient flap sites.

Figures in this Article

The forearm fasciocutaneous flap based on the radial or ulnar artery is a favored flap in microvascular head and neck reconstruction because of its pliability, its reliability of harvest, and its versatility.1,2 A major disadvantage of this flap, however, is the conspicuous donor site defect that commonly requires repair with a split-thickness skin graft (STSG) harvested from a secondary site.3,4 Split-thickness skin grafts harvested from secondary donor sites can be associated with pain, delayed healing, infection, scarring, and poor aesthetic changes.5,6 To minimize secondary donor site changes, full-thickness skin grafts and pedicled transposition flaps from the proximal aspect of the forearm have been suggested.7,8 The proximal aspect of the forearm is, however, a limited donor site when large forearm defects require closure. To avoid secondary graft sites, artificial dermis also has been used in repairing the radial forearm free flap (RFFF) donor defect.9 An alternative source of skin for resurfacing the RFFF defect is an STSG harvested from the primary forearm donor site.10,11 In this article, we report a technical modification in the harvest and application of STSGs in the repair of forearm donor defects.

In 16 consecutive patients who underwent an RFFF for reconstruction of various oral or pharyngeal defects, a hinged forearm STSG was used for donor site repair. Written informed consent was obtained from all patients. These patients were prospectively reviewed for successful skin graft harvest, graft survival, color match, scarring along the hinge line, and luminal scarring.

All RFFFs in this group of patients were harvested without tourniquet control. With the forearm exposed, the radial arterial pulse was palpated and outlined. The desired fasciocutaneous flap was designed centered on the radial artery. The flap dissection starts proximally with identification and mobilization of the radial artery and accompanying venae comitantes. A dermatome blade guard slightly wider than the width of the designed skin island was selected (Figure 1). Split-thickness skin grafts 0.016-to 0.018-in thick were harvested with a powered dermatome (Zimmer Holdings, Inc, Warsaw, Indiana). The skin grafts were raised and left-hinged along one of the short or long margins, depending on the flap design (see the video). Constant pressure at approximately a 45° angle to the skin surface was exerted on the dermatome throughout the harvest. The dermatome blade was deactivated at the hinge line to prevent inadvertent injury to the graft attachment. The elevated STSGs were covered with moist gauze and kept hydrated until they were ready to be applied. Then, the RFFFs were harvested in a subfascial plane in a routine manner, changing to a suprafascial level over the tendons. The donor site defects were repaired by replacing the hinged STSGs. The STSGs were not meshed in any of the cases. The STSGs were immobilized for 5 to 7 days with a continuous vacuum-assisted suction device (Figure 1). Graft viability was visually assessed on postoperative days 5 to 7 after the retention bolsters were removed. Herein, successful harvest of a hinged STSG is defined as the ability to raise the STSG without disruption, keeping it pedicled to the adjacent skin. The viability of the skin graft on the forearm was determined on postoperative day 7. Graft viability was recorded by the principal author (K.B.) after visual inspection as a percentage of the defect covered by viable skin without exposure of the underlying defect.

Place holder to copy figure label and caption
Graphic Jump Location

Figure 1. Harvest, application, and immobilization of the hinged split-thickness skin graft for radial forearm free flap repair (A and B).

In all 16 patients, a hinged STSG was successfully harvested from the forearm. The mean (SD) defect size was 53.7 (29.9) cm2. Complete repair of the forearm defect was achieved in 14 of 16 patients (88%) using only the hinged STSG. In 2 patients whose initially designed RFFFs were enlarged after the hinged STSG had been harvested, an additional 2-cm strip of STSG was harvested from the thigh to allow complete closure of the forearm defect. We observed 90% or greater graft survival in all cases at the seventh postoperative day. One patient had an exposed tendon that healed secondarily from conservative measures. Assessment of the forearm donor site between 1 and 3 months after the primary surgical procedure showed complete defect coverage, acceptable color match, and no scarring along the graft hinge line (Figure 2). For the oral defects, the partly deepithelialized RFFFs completely reepithelialized with excellent mucosal and flap color match (Figure 2). In 1 African American patient, punctuate areas of hyperpigmentation within a mostly pink-looking neo tongue were observed. No flap loss and no luminal scarring in tubed pharyngoesophageal flaps were observed.

Place holder to copy figure label and caption
Graphic Jump Location

Figure 2. Radial forearm flap donor site repaired with a hinged split-thickness skin graft showing excellent color match and reduced scarring at the forearm (A). A good flap (recipient color match within the oral cavity) is achieved (B).

We have presented a technical modification in the harvest and application of STSGs harvested from the primary donor sites of fasciocutaneous flaps for the repair of resulting donor site defects. In all previous descriptions of STSG harvest from the forearm flap donor sites, the grafts were detached completely. We have found that leaving the harvested STSG pedicled keeps the graft properly oriented; minimizes initial graft curling, contraction, and disruption; and spares additional scarring along the hinge site. The graft survival with this modified hinge technique is greater than 90% and is associated with few complications.

Although attached to adjacent skin that is perfused, a hinged STSG of thin to intermediate thickness (0.001-0.018 in) is not a vascularized flap and depends on early imbibition and neovascularization for graft survival. Therefore, a supportive tissue bed, particularly over the flexor tendons, is necessary for graft viability. Suprafascial dissection over the tendons and oversewing of the flexor tendon with the long flexor muscle of the thumb and the superficial flexor muscle of the fingers has been reported to improve STSG healing.12 Raising a thick-hinged STSG on the forearm leaves a thin dermal layer on a mostly fascial flap and may preserve the subcutaneous vascular network, which reliably supplies the forearm skin by means of numerous longitudinal and transverse anastomoses.13

The technique used in harvesting skin from the forearm is similar to that generally used in other donor sites. The forearm is, however, convex and may not allow proper contact with the dermatome blade. Often, a dermatome blade guard slightly wider than the width of the planned flap is necessary because the outer edges of the blade do not make good skin contact.

Harvesting STSGs from a planned fasciocutaneous flap donor site has been described previously11,14 for the forearm and fibula flap donor sites. The major advantage of this approach is the avoidance of a secondary donor defect that heals by reepithelialization. An additional benefit is the color match at the forearm and the flap recipient site. Early monitoring of partially deepithelialized fasciocutaneous flaps may be challenging. Punctate bleeding from the disrupted papillary vessels occurs. Soon, this early bleeding is replaced by the appearance of a fibrinous layer, which may make it difficult to assess the flap by color. Rubbing the flap with hydrogen peroxide restarts the punctate bleeding. Other flap monitoring measures, such as direct Doppler imaging of vessels on the skin paddle, flap warmth, use of implanted Doppler imaging, and surface flap oximeter, are helpful.

The thickness of the forearm skin has been reported to remain relatively constant until the seventh decade of life, after which time it diminishes.15 Therefore, although STSGs as thick as 0.018 in may be harvested safely from the forearm in most patients, thinner skin grafts should be considered in patients 70 years and older.

The exposed dermis in adjacent deepithelialized skin flaps are at risk of scarring together. In tubed pharyngeal flaps, intraluminal scarring will lead to stenosis and will impair swallowing. Thus, caution should be exercised in the design and application of deepithelialized flaps in tubed reconstructions. Two patients in this series who had tubed pharyngoesophageal reconstructions have had clear swallow evaluations and continue to tolerate oral intake without evidence of luminal narrowing.

The hinged STSG harvested from the forearm is a reliable method of repairing RFFF donor site defects and offers the advantages of reduced suture line scarring, minimized STSG disruption, no secondary donor site morbidity, and good color match at the donor and recipient flap sites.

Correspondence: Kofi Boahene, MD, Department of Otolaryngology–Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 N Caroline St, Sixth Floor, Johns Hopkins Outpatient Center, Baltimore, MD 21287 (Dboahen1@jhmi.edu).

Accepted for Publication: June 3, 2011.

Author Contributions:Study concept and design: Boahene. Acquisition of data: Boahene and Byrne. Analysis and interpretation of data: Boahene, Richmon, and Ishii. Drafting of the manuscript: Boahene and Ishii. Critical revision of the manuscript for important intellectual content: Boahene, Richmon, Byrne, and Ishii. Administrative, technical, and material support: Boahene. Study supervision: Richmon and Byrne.

Financial Disclosure: None reported.

Online-Only Material: A video is available here.

Soutar DS, Scheker LR, Tanner NS, McGregor IA. The radial forearm flap: a versatile method for intra-oral reconstruction.  Br J Plast Surg. 1983;36(1):1-8
PubMed   |  Link to Article
Soutar DS, Ray AK. The radial forearm flap in head and neck reconstruction. In: Jackson IT, Summerlad BC, eds. Recent Advances in Plastic Surgery. Vol. 4. Edinburgh, Scotland: Churchill Livingston: 1992;77-91
Brown MT, Cheney ML, Gliklich RL, Sheffler LR, Varvares MA. Assessment of functional morbidity in the radial forearm free flap donor site.  Arch Otolaryngol Head Neck Surg. 1996;122(9):991-994
PubMed   |  Link to Article
de Bree R, Hartley C, Smeele LE, Kuik DJ, Quak JJ, Leemans CR. Evaluation of donor site function and morbidity of the fasciocutaneous radial forearm flap.  Laryngoscope. 2004;114(11):1973-1976
PubMed   |  Link to Article
Martinot V, Mitchell V, Fevrier P, Duhamel A, Pellerin P. Comparative study of split thickness skin grafts taken from the scalp and thigh in children.  Burns. 1994;20(2):146-150
PubMed   |  Link to Article
Fatah MF, Ward CM. The morbidity of split-skin graft donor sites in the elderly: the case for mesh-grafting the donor site.  Br J Plast Surg. 1984;37(2):184-190
PubMed   |  Link to Article
Bashir MA, Fung V, Kernohan MD, Ragbir M, Ahmed OA. “Z-plasty” modification of ulnar-based fasciocutaneous flap for closure of the radial forearm flap donor defect.  Ann Plast Surg. 2010;64(1):22-23
PubMed   |  Link to Article
González-García R, Ruiz-Laza L, Manzano D, Monje F. Combined local triangular full-thickness skin graft for the closure of the radial forearm free flap donor site: a new technique.  Plast Reconstr Surg. 2010;125(2):85e-86eLink to Article
PubMed   |  Link to Article
Lee J-W, Jang Y-C, Oh S-J. Use of the artificial dermis for free radial forearm flap donor site.  Ann Plast Surg. 2005;55(5):500-502
PubMed   |  Link to Article
Xavier TS, Lamb DW. The forearm as donor site for split skin grafts.  Hand. 1974;6(3):243-246
PubMed   |  Link to Article
Ghanem TA, Wax MK. A novel split–thickness skin graft donor site: the radial skin paddle. Otolaryngol Head Neck Surg. 2009;141(3):390-394
Fenton OM, Roberts JO. Improving the donor site of the radial forearm flap.  Br J Plast Surg. 1985;38(4):504-505
PubMed   |  Link to Article
Weinzweig N, Chen L, Chen Z-W. The distally based radial forearm fasciosubcutaneous flap with preservation of the radial artery: an anatomic and clinical approach.  Plast Reconstr Surg. 1994;94(5):675-684
PubMed   |  Link to Article
Kim PD, Fleck T, Heffelfinger R, Blackwell KE. Avoiding secondary skin graft donor site morbidity in the fibula free flap harvest.  Arch Otolaryngol Head Neck Surg. 2008;134(12):1324-1327
PubMed   |  Link to Article
de Rigal J, Escoffier C, Querleux B, Faivre B, Agache P, Lévêque J-L. Assessment of aging of the human skin by in vivo ultrasonic imaging.  J Invest Dermatol. 1989;93(5):621-625
Link to Article

Figures

Place holder to copy figure label and caption
Graphic Jump Location

Figure 1. Harvest, application, and immobilization of the hinged split-thickness skin graft for radial forearm free flap repair (A and B).

Place holder to copy figure label and caption
Graphic Jump Location

Figure 2. Radial forearm flap donor site repaired with a hinged split-thickness skin graft showing excellent color match and reduced scarring at the forearm (A). A good flap (recipient color match within the oral cavity) is achieved (B).

Tables

References

Soutar DS, Scheker LR, Tanner NS, McGregor IA. The radial forearm flap: a versatile method for intra-oral reconstruction.  Br J Plast Surg. 1983;36(1):1-8
PubMed   |  Link to Article
Soutar DS, Ray AK. The radial forearm flap in head and neck reconstruction. In: Jackson IT, Summerlad BC, eds. Recent Advances in Plastic Surgery. Vol. 4. Edinburgh, Scotland: Churchill Livingston: 1992;77-91
Brown MT, Cheney ML, Gliklich RL, Sheffler LR, Varvares MA. Assessment of functional morbidity in the radial forearm free flap donor site.  Arch Otolaryngol Head Neck Surg. 1996;122(9):991-994
PubMed   |  Link to Article
de Bree R, Hartley C, Smeele LE, Kuik DJ, Quak JJ, Leemans CR. Evaluation of donor site function and morbidity of the fasciocutaneous radial forearm flap.  Laryngoscope. 2004;114(11):1973-1976
PubMed   |  Link to Article
Martinot V, Mitchell V, Fevrier P, Duhamel A, Pellerin P. Comparative study of split thickness skin grafts taken from the scalp and thigh in children.  Burns. 1994;20(2):146-150
PubMed   |  Link to Article
Fatah MF, Ward CM. The morbidity of split-skin graft donor sites in the elderly: the case for mesh-grafting the donor site.  Br J Plast Surg. 1984;37(2):184-190
PubMed   |  Link to Article
Bashir MA, Fung V, Kernohan MD, Ragbir M, Ahmed OA. “Z-plasty” modification of ulnar-based fasciocutaneous flap for closure of the radial forearm flap donor defect.  Ann Plast Surg. 2010;64(1):22-23
PubMed   |  Link to Article
González-García R, Ruiz-Laza L, Manzano D, Monje F. Combined local triangular full-thickness skin graft for the closure of the radial forearm free flap donor site: a new technique.  Plast Reconstr Surg. 2010;125(2):85e-86eLink to Article
PubMed   |  Link to Article
Lee J-W, Jang Y-C, Oh S-J. Use of the artificial dermis for free radial forearm flap donor site.  Ann Plast Surg. 2005;55(5):500-502
PubMed   |  Link to Article
Xavier TS, Lamb DW. The forearm as donor site for split skin grafts.  Hand. 1974;6(3):243-246
PubMed   |  Link to Article
Ghanem TA, Wax MK. A novel split–thickness skin graft donor site: the radial skin paddle. Otolaryngol Head Neck Surg. 2009;141(3):390-394
Fenton OM, Roberts JO. Improving the donor site of the radial forearm flap.  Br J Plast Surg. 1985;38(4):504-505
PubMed   |  Link to Article
Weinzweig N, Chen L, Chen Z-W. The distally based radial forearm fasciosubcutaneous flap with preservation of the radial artery: an anatomic and clinical approach.  Plast Reconstr Surg. 1994;94(5):675-684
PubMed   |  Link to Article
Kim PD, Fleck T, Heffelfinger R, Blackwell KE. Avoiding secondary skin graft donor site morbidity in the fibula free flap harvest.  Arch Otolaryngol Head Neck Surg. 2008;134(12):1324-1327
PubMed   |  Link to Article
de Rigal J, Escoffier C, Querleux B, Faivre B, Agache P, Lévêque J-L. Assessment of aging of the human skin by in vivo ultrasonic imaging.  J Invest Dermatol. 1989;93(5):621-625
Link to Article

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